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Evaluation of a Novel Assay for Detection of the Fetal Marker RASSF1A: Facilitating Improved Diagnostic Reliability of Noninvasive Prenatal Diagnosis
BACKGROUND: Analysis of cell free fetal (cff) DNA in maternal plasma is used routinely for non invasive prenatal diagnosis (NIPD) of fetal sex determination, fetal rhesus D status and some single gene disorders. True positive results rely on detection of the fetal target being analysed. No amplifica...
Autores principales: | White, Helen E., Dent, Carolyn L., Hall, Victoria J., Crolla, John A., Chitty, Lyn S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443218/ https://www.ncbi.nlm.nih.gov/pubmed/23024794 http://dx.doi.org/10.1371/journal.pone.0045073 |
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