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Histone Deacetylase Inhibitors Induce Epithelial-to-Mesenchymal Transition in Prostate Cancer Cells

Clinical experience of histone deacetylase inhibitors (HDACIs) in patients with solid tumors has been disappointing; however, the molecular mechanism of treatment failure is not known. Therefore, we sought to investigate the molecular mechanism of treatment failure of HDACIs in the present study. We...

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Detalles Bibliográficos
Autores principales: Kong, Dejuan, Ahmad, Aamir, Bao, Bin, Li, Yiwei, Banerjee, Sanjeev, Sarkar, Fazlul H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443231/
https://www.ncbi.nlm.nih.gov/pubmed/23024790
http://dx.doi.org/10.1371/journal.pone.0045045