Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas

Mutations in the critical chromatin modifier ATRX and mutations in CIC and FUBP1, which are potent regulators of cell growth, have been discovered in specific subtypes of gliomas, the most common type of primary malignant brain tumors. However, the frequency of these mutations in many subtypes of gl...

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Detalles Bibliográficos
Autores principales: Jiao, Yuchen, Killela, Patrick J., Reitman, Zachary J., Rasheed, B. Ahmed, Heaphy, Christopher M., de Wilde, Roeland F., Rodriguez, Fausto J., Rosemberg, Sergio, Oba-Shinjo, Sueli Mieko, Marie, Suely Kazue Nagahashi, Bettegowda, Chetan, Agrawal, Nishant, Lipp, Eric, Pirozzi, Christopher J., Lopez, Giselle Y., He, Yiping, Friedman, Henry S., Friedman, Allan H., Riggins, Gregory J., Holdhoff, Matthias, Burger, Peter, McLendon, Roger E., Bigner, Darell D., Vogelstein, Bert, Meeker, Alan K., Kinzler, Kenneth W., Papadopoulos, Nickolas, Diaz, Luis A., Yan, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443254/
https://www.ncbi.nlm.nih.gov/pubmed/22869205

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