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The Rad1–Rad10 nuclease promotes chromosome translocations between dispersed repeats

Holliday junctions can be formed during homology-dependent repair of DNA double-strand breaks and their resolution is essential for chromosome segregation and generation of crossover products. The Mus81–Mms4 and Yen1 nucleases are required for mitotic crossovers between chromosome homologs in Saccha...

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Detalles Bibliográficos
Autores principales: Mazón, Gerard, Lam, Alicia F., Ho, Chu Kwen, Kupiec, Martin, Symington, Lorraine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443319/
https://www.ncbi.nlm.nih.gov/pubmed/22885325
http://dx.doi.org/10.1038/nsmb.2359