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The Rad1–Rad10 nuclease promotes chromosome translocations between dispersed repeats
Holliday junctions can be formed during homology-dependent repair of DNA double-strand breaks and their resolution is essential for chromosome segregation and generation of crossover products. The Mus81–Mms4 and Yen1 nucleases are required for mitotic crossovers between chromosome homologs in Saccha...
Autores principales: | Mazón, Gerard, Lam, Alicia F., Ho, Chu Kwen, Kupiec, Martin, Symington, Lorraine S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443319/ https://www.ncbi.nlm.nih.gov/pubmed/22885325 http://dx.doi.org/10.1038/nsmb.2359 |
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