Role of obesity in a randomized placebo-controlled trial of difluoromethylornithine (DFMO) + sulindac for the prevention of sporadic colorectal adenomas

BACKGROUND: Chemoprevention with the polyamine-inhibitory regimen difluoromethylornithine (DFMO) + sulindac markedly reduces risk of recurrent adenoma in colorectal adenoma patients. Obesity is associated with risk of colorectal adenoma and colorectal cancer. This study investigates how obesity infl...

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Detalles Bibliográficos
Autores principales: Zell, Jason A., Lin, Bruce S., Madson, Nikki, McLaren, Christine E., Gerner, Eugene W., Meyskens, Frank L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443348/
https://www.ncbi.nlm.nih.gov/pubmed/22907422
http://dx.doi.org/10.1007/s10552-012-0051-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443348/
https://www.ncbi.nlm.nih.gov/pubmed/22907422
http://dx.doi.org/10.1007/s10552-012-0051-6

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