The catalytic and the RNA subunits of human telomerase are required to immortalize equid primary fibroblasts

Many human primary somatic cells can be immortalized by inducing telomerase activity through the exogenous expression of the human telomerase catalytic subunit (hTERT). This approach has been extended to the immortalization of cell lines from several mammals. Here, we show that hTERT expression is n...

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Detalles Bibliográficos
Autores principales: Vidale, Pamela, Magnani, Elisa, Nergadze, Solomon G., Santagostino, Marco, Cristofari, Gael, Smirnova, Alexandra, Mondello, Chiara, Giulotto, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443485/
https://www.ncbi.nlm.nih.gov/pubmed/22797876
http://dx.doi.org/10.1007/s00412-012-0379-4

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