Proximal tubule sphingosine kinase-1 has a critical role in A1 adenosine receptor-mediated renal protection from ischemia

Renal ischemia reperfusion injury is a major cause of acute kidney injury. We previously found that renal A1 adenosine receptor (A1AR) activation attenuated multiple cell death pathways including necrosis, apoptosis and inflammation. Here, we tested whether induction of cytoprotective sphingosine ki...

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Detalles Bibliográficos
Autores principales: Park, Sang Won, Kim, Mihwa, Kim, Joo Yun, Brown, Kevin M., Haase, Volker H., D’Agati, Vivette D., Lee, H. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443517/
https://www.ncbi.nlm.nih.gov/pubmed/22695326
http://dx.doi.org/10.1038/ki.2012.224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443517/
https://www.ncbi.nlm.nih.gov/pubmed/22695326
http://dx.doi.org/10.1038/ki.2012.224

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