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Loss of CD103+ DCs and Mucosal IL-17+ and IL-22+ Lymphocytes is Associated with Mucosal Damage in SIV Infection
HIV/SIV disease progression is associated with multifocal damage to the GI tract epithelial barrier that correlates with microbial translocation and persistent pathological immune activation but the underlying mechanisms remain unclear. Investigating alterations in mucosal immunity during SIV infect...
Autores principales: | Klatt, Nichole R., Estes, Jacob D., Sun, Xiaoyong, Ortiz, Alexandra M., Barber, John S., Harris, Levelle D., Cervasi, Barbara, Yokomizo, Lauren K., Pan, Li, Vinton, Carol L., Tabb, Brian, Canary, Lauren A., Dang, Que, Hirsch, Vanessa M., Alter, Galit, Belkaid, Yasmine, Lifson, Jeffrey D., Silvestri, Guido, Milner, Joshua D., Paiardini, Mirko, Haddad, Elias K., Brenchley, Jason M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443541/ https://www.ncbi.nlm.nih.gov/pubmed/22643849 http://dx.doi.org/10.1038/mi.2012.38 |
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