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TROP2 is epigenetically inactivated and modulates IGF-1R signalling in lung adenocarcinoma

Trop-2, a cell surface glycoprotein, contains both extracellular epidermal growth factor-like and thyroglobulin type-1 repeat domains. Low TROP2 expression was observed in lung adenocarcinoma tissues as compared with their normal counterparts. The lack of expression could be due to either the loss o...

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Detalles Bibliográficos
Autores principales:	Lin, Jau-Chen, Wu, Yi-Ying, Wu, Jing-Yi, Lin, Tzu-Chieh, Wu, Chen-Tu, Chang, Yih-Leong, Jou, Yuh-Shan, Hong, Tse-Ming, Yang, Pan-Chyr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443948/ https://www.ncbi.nlm.nih.gov/pubmed/22419550 http://dx.doi.org/10.1002/emmm.201200222

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