Human Antibodies Can Cross Guinea Pig Placenta and Bind Its Neonatal Fc Receptor: Implications for Studying Immune Prophylaxis and Therapy during Pregnancy

Despite increased use of monoclonal and polyclonal antibody therapies, including during pregnancy, there is little data on appropriate animal models that could humanely be used to understand determinants of protection and to evaluate safety of these biologics in the mother and the developing fetus....

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Detalles Bibliográficos
Autores principales: Struble, Evi Budo, Ma, Li, Zhong, Lilin, Lesher, A., Beren, Joel, Zhang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444053/
https://www.ncbi.nlm.nih.gov/pubmed/22991567
http://dx.doi.org/10.1155/2012/538701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444053/
https://www.ncbi.nlm.nih.gov/pubmed/22991567
http://dx.doi.org/10.1155/2012/538701

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