A Portable and Power-Free Microfluidic Device for Rapid and Sensitive Lead (Pb(2+)) Detection

A portable and power-free microfluidic device was designed for rapid and sensitive detection of lead (Pb(2+)). 11-mercaptoundecanoic acid (MUA)-functionalized gold nanoparticles (MUA-AuNPs) aggregated in the presence of Pb(2+) for the chelation mechanism. When we performed this analysis on a polydim...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Chunhui, He, Shijiang, Liu, Gang, Wang, Lianhui, Song, Shiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444111/
https://www.ncbi.nlm.nih.gov/pubmed/23012553
http://dx.doi.org/10.3390/s120709467
_version_ 1782243636609548288
author Fan, Chunhui
He, Shijiang
Liu, Gang
Wang, Lianhui
Song, Shiping
author_facet Fan, Chunhui
He, Shijiang
Liu, Gang
Wang, Lianhui
Song, Shiping
author_sort Fan, Chunhui
collection PubMed
description A portable and power-free microfluidic device was designed for rapid and sensitive detection of lead (Pb(2+)). 11-mercaptoundecanoic acid (MUA)-functionalized gold nanoparticles (MUA-AuNPs) aggregated in the presence of Pb(2+) for the chelation mechanism. When we performed this analysis on a polydimethylsiloxane (PDMS) microfluidic chip, the aggregations deposited onto the surface of chip and formed dark lines along the laminar flows in the zigzag microchannels. This visual result can be observed by the naked eye through a microscope or just a drop of water as a magnifier. Ten μM Pb(2+) was successfully detected.
format Online
Article
Text
id pubmed-3444111
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Molecular Diversity Preservation International (MDPI)
record_format MEDLINE/PubMed
spelling pubmed-34441112012-09-25 A Portable and Power-Free Microfluidic Device for Rapid and Sensitive Lead (Pb(2+)) Detection Fan, Chunhui He, Shijiang Liu, Gang Wang, Lianhui Song, Shiping Sensors (Basel) Article A portable and power-free microfluidic device was designed for rapid and sensitive detection of lead (Pb(2+)). 11-mercaptoundecanoic acid (MUA)-functionalized gold nanoparticles (MUA-AuNPs) aggregated in the presence of Pb(2+) for the chelation mechanism. When we performed this analysis on a polydimethylsiloxane (PDMS) microfluidic chip, the aggregations deposited onto the surface of chip and formed dark lines along the laminar flows in the zigzag microchannels. This visual result can be observed by the naked eye through a microscope or just a drop of water as a magnifier. Ten μM Pb(2+) was successfully detected. Molecular Diversity Preservation International (MDPI) 2012-07-10 /pmc/articles/PMC3444111/ /pubmed/23012553 http://dx.doi.org/10.3390/s120709467 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Fan, Chunhui
He, Shijiang
Liu, Gang
Wang, Lianhui
Song, Shiping
A Portable and Power-Free Microfluidic Device for Rapid and Sensitive Lead (Pb(2+)) Detection
title A Portable and Power-Free Microfluidic Device for Rapid and Sensitive Lead (Pb(2+)) Detection
title_full A Portable and Power-Free Microfluidic Device for Rapid and Sensitive Lead (Pb(2+)) Detection
title_fullStr A Portable and Power-Free Microfluidic Device for Rapid and Sensitive Lead (Pb(2+)) Detection
title_full_unstemmed A Portable and Power-Free Microfluidic Device for Rapid and Sensitive Lead (Pb(2+)) Detection
title_short A Portable and Power-Free Microfluidic Device for Rapid and Sensitive Lead (Pb(2+)) Detection
title_sort portable and power-free microfluidic device for rapid and sensitive lead (pb(2+)) detection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444111/
https://www.ncbi.nlm.nih.gov/pubmed/23012553
http://dx.doi.org/10.3390/s120709467
work_keys_str_mv AT fanchunhui aportableandpowerfreemicrofluidicdeviceforrapidandsensitiveleadpb2detection
AT heshijiang aportableandpowerfreemicrofluidicdeviceforrapidandsensitiveleadpb2detection
AT liugang aportableandpowerfreemicrofluidicdeviceforrapidandsensitiveleadpb2detection
AT wanglianhui aportableandpowerfreemicrofluidicdeviceforrapidandsensitiveleadpb2detection
AT songshiping aportableandpowerfreemicrofluidicdeviceforrapidandsensitiveleadpb2detection
AT fanchunhui portableandpowerfreemicrofluidicdeviceforrapidandsensitiveleadpb2detection
AT heshijiang portableandpowerfreemicrofluidicdeviceforrapidandsensitiveleadpb2detection
AT liugang portableandpowerfreemicrofluidicdeviceforrapidandsensitiveleadpb2detection
AT wanglianhui portableandpowerfreemicrofluidicdeviceforrapidandsensitiveleadpb2detection
AT songshiping portableandpowerfreemicrofluidicdeviceforrapidandsensitiveleadpb2detection

Ejemplares similares