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Regulation and physiological roles of the calpain system in muscular disorders
Calpains, a family of Ca(2+)-dependent cytosolic cysteine proteases, can modulate their substrates' structure and function through limited proteolytic activity. In the human genome, there are 15 calpain genes. The most-studied calpains, referred to as conventional calpains, are ubiquitous. Whil...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444232/ https://www.ncbi.nlm.nih.gov/pubmed/22542715 http://dx.doi.org/10.1093/cvr/cvs157 |