Local Effects of Regulatory T Cells in MUC1 Transgenic Mice Potentiate Growth of MUC1 Expressing Tumor Cells In Vivo

MUC1 transgenic (MUC1.Tg) mice have widely been used as model recipients of cancer immunotherapy with MUC1. Although MUC1.Tg mice have previously been shown to be immunologically tolerant to MUC1, the involvement of regulatory T (Treg) cells in this phenotype remains unclear. Here, we showed that nu...

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Detalles Bibliográficos
Autores principales: Sugiura, Daisuke, Denda-Nagai, Kaori, Takashima, Mitsuyo, Murakami, Ryuichi, Nagai, Shigenori, Takeda, Kazuyoshi, Irimura, Tatsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444443/
https://www.ncbi.nlm.nih.gov/pubmed/23028615
http://dx.doi.org/10.1371/journal.pone.0044770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444443/
https://www.ncbi.nlm.nih.gov/pubmed/23028615
http://dx.doi.org/10.1371/journal.pone.0044770

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