NOTCH1, HIF1A and Other Cancer-Related Proteins in Lung Tissue from Uranium Miners—Variation by Occupational Exposure and Subtype of Lung Cancer

BACKGROUND: Radon and arsenic are established pulmonary carcinogens. We investigated the association of cumulative exposure to these carcinogens with NOTCH1, HIF1A and other cancer-specific proteins in lung tissue from uranium miners. METHODOLOGY/PRINCIPAL FINDINGS: Paraffin-embedded tissue of 147 m...

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Detalles Bibliográficos
Autores principales: Pesch, Beate, Casjens, Swaantje, Stricker, Ingo, Westerwick, Daniela, Taeger, Dirk, Rabstein, Sylvia, Wiethege, Thorsten, Tannapfel, Andrea, Brüning, Thomas, Johnen, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444449/
https://www.ncbi.nlm.nih.gov/pubmed/23028920
http://dx.doi.org/10.1371/journal.pone.0045305

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