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Detrimental Effects of RNAi: A Cautionary Note on Its Use in Drosophila Ageing Studies

RNA interference (RNAi) provides an important tool for gene function discovery. It has been widely exploited in Caenorhabditis elegans ageing research because it does not appear to have any non-specific effects on ageing-related traits in that model organism. We show here that ubiquitous, adult-onse...

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Detalles Bibliográficos
Autores principales: Alic, Nazif, Hoddinott, Matthew P., Foley, Andrea, Slack, Cathy, Piper, Matthew D. W., Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444450/
https://www.ncbi.nlm.nih.gov/pubmed/23028964
http://dx.doi.org/10.1371/journal.pone.0045367

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