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Detrimental Effects of RNAi: A Cautionary Note on Its Use in Drosophila Ageing Studies
RNA interference (RNAi) provides an important tool for gene function discovery. It has been widely exploited in Caenorhabditis elegans ageing research because it does not appear to have any non-specific effects on ageing-related traits in that model organism. We show here that ubiquitous, adult-onse...
Autores principales: | Alic, Nazif, Hoddinott, Matthew P., Foley, Andrea, Slack, Cathy, Piper, Matthew D. W., Partridge, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444450/ https://www.ncbi.nlm.nih.gov/pubmed/23028964 http://dx.doi.org/10.1371/journal.pone.0045367 |
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