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Differential Effects of Lovastatin on Cisplatin Responses in Normal Human Mesothelial Cells versus Cancer Cells: Implication for Therapy

The cancer killing efficacy of standard chemotherapeutic agents such as cisplatin (CDDP) is limited by their side effects to normal tissues. Therefore, research efforts optimizing the safety and efficacy of those agents are clinically relevant. We did screen for agents that specifically protect norm...

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Detalles Bibliográficos
Autores principales: Shi, Yandong, Felley-Bosco, Emanuela, Marti, Thomas M., Stahel, Rolf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444484/
https://www.ncbi.nlm.nih.gov/pubmed/23028957
http://dx.doi.org/10.1371/journal.pone.0045354

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