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Differential Effects of Lovastatin on Cisplatin Responses in Normal Human Mesothelial Cells versus Cancer Cells: Implication for Therapy
The cancer killing efficacy of standard chemotherapeutic agents such as cisplatin (CDDP) is limited by their side effects to normal tissues. Therefore, research efforts optimizing the safety and efficacy of those agents are clinically relevant. We did screen for agents that specifically protect norm...
Autores principales: | Shi, Yandong, Felley-Bosco, Emanuela, Marti, Thomas M., Stahel, Rolf A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444484/ https://www.ncbi.nlm.nih.gov/pubmed/23028957 http://dx.doi.org/10.1371/journal.pone.0045354 |
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