Cargando…

Aging Effect on Neurotrophic Activity of Human Mesenchymal Stem Cells

Clinical efficacy of stem cells for nerve repair is likely to be influenced by issues including donor age and in vitro expansion time. We isolated human mesenchymal stem cells (MSC) from bone marrow of young (16–18 years) and old (67–75 years) donors and analyzed their capacity to differentiate and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brohlin, Maria, Kingham, Paul J., Novikova, Liudmila N., Novikov, Lev N., Wiberg, Mikael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444498/ https://www.ncbi.nlm.nih.gov/pubmed/23028757 http://dx.doi.org/10.1371/journal.pone.0045052

Ejemplares similares

Long-Term Effects of Fibrin Conduit with Human Mesenchymal Stem Cells and Immunosuppression after Peripheral Nerve Repair in a Xenogenic Model
por: McGrath, Aleksandra M., et al.
Publicado: (2018)

The neurotrophic effects of different human dental mesenchymal stem cells
por: Kolar, Mallappa K., et al.
Publicado: (2017)

Neuroprotective Effects of N-Acetyl-Cysteine and Acetyl-L-Carnitine after Spinal Cord Injury in Adult Rats
por: Karalija, Amar, et al.
Publicado: (2012)

Regenerative effects of human embryonic stem cell‐derived neural crest cells for treatment of peripheral nerve injury
por: Jones, Iwan, et al.
Publicado: (2018)

Effect of Delayed Peripheral Nerve Repair on Nerve Regeneration, Schwann Cell Function and Target Muscle Recovery
por: Jonsson, Samuel, et al.
Publicado: (2013)

Human Embryonic Stem Cell–derived Neural Crest Cells Promote Sprouting and Motor Recovery Following Spinal Cord Injury in Adult Rats
por: Jones, Iwan, et al.
Publicado: (2021)

Efficacy of Nerve-Derived Hydrogels to Promote Axon Regeneration Is Influenced by the Method of Tissue Decellularization
por: Kuna, Vijay Kumar, et al.
Publicado: (2022)

Differentiation of Pre- and Postganglionic Nerve Injury Using MRI of the Spinal Cord
por: Karalija, Amar, et al.
Publicado: (2016)

Investigation of the Expression of Myogenic Transcription Factors, microRNAs and Muscle-Specific E3 Ubiquitin Ligases in the Medial Gastrocnemius and Soleus Muscles following Peripheral Nerve Injury
por: Wiberg, Rebecca, et al.
Publicado: (2015)

In Vitro Osteogenic Differentiation of Human Mesenchymal Stem Cells from Jawbone Compared with Dental Tissue
por: Pettersson, Linda F., et al.
Publicado: (2017)

Platelet lysate for expansion or osteogenic differentiation of bone marrow mesenchymal stem cells for 3D tissue constructs
por: Anerillas, Luis Oliveros, et al.
Publicado: (2023)

Three-Dimensional Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells Promotes Matrix Metallopeptidase 13 (MMP13) Expression in Type I Collagen Hydrogels
por: Oliveros Anerillas, Luis, et al.
Publicado: (2021)

Schwann cell-like differentiated adipose stem cells promote neurite outgrowth via secreted exosomes and RNA transfer
por: Ching, Rosanna C, et al.
Publicado: (2018)

Development and validation of an in vitro model system to study peripheral sensory neuron development and injury
por: Jones, Iwan, et al.
Publicado: (2018)

Safety of repeated transplantations of neurotrophic factors-secreting human mesenchymal stromal stem cells
por: Gothelf, Yael, et al.
Publicado: (2014)

Effects on Proliferation and Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells Engineered to Express Neurotrophic Factors
por: Wang, Yi, et al.
Publicado: (2016)

Evaluation of neurotrophic factor secreting mesenchymal stem cells in progressive multiple sclerosis
por: Cohen, Jeffrey A, et al.
Publicado: (2022)

Bioprinted Schwann and Mesenchymal Stem Cell Co-Cultures for Enhanced Spatial Control of Neurite Outgrowth
por: Alakpa, Enateri V., et al.
Publicado: (2023)

Brain-derived neurotrophic factor gene-modified bone marrow mesenchymal stem cells
por: HAN, ZHONG-MIN, et al.
Publicado: (2015)

miRNA profiling of NurOwn®: mesenchymal stem cells secreting neurotrophic factors
por: Gothelf, Yael, et al.
Publicado: (2017)

Hypoxia, a dynamic tool to amplify the gingival mesenchymal stem cells potential for neurotrophic factor secretion
por: Patil, Shankargouda, et al.
Publicado: (2022)

Brain-Derived Neurotrophic Factor Secreting Human Mesenchymal Stem Cells Improve Outcomes in Rett Syndrome Mouse Models
por: Kim, Hyo Jeong, et al.
Publicado: (2021)

Effect of mesenchymal stem cell transplantation on brain-derived neurotrophic factor expression in rats with Tourette syndrome
por: LIU, XIUMEI, et al.
Publicado: (2016)

Brain Derived Neurotrophic Factor and Glial Cell Line-Derived Neurotrophic Factor-Transfected Bone Mesenchymal Stem Cells for the Repair of Periphery Nerve Injury
por: Zhang, Qiang, et al.
Publicado: (2020)

Guiding the osteogenic fate of mouse and human mesenchymal stem cells through feedback system control
por: Honda, Yoshitomo, et al.
Publicado: (2013)

An In Vitro Comparison of the Neurotrophic and Angiogenic Activity of Human and Canine Adipose-Derived Mesenchymal Stem Cells (MSCs): Translating MSC-Based Therapies for Spinal Cord Injury
por: Delfi, Ibtesam R. T. Al, et al.
Publicado: (2020)

Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington's Disease Mouse Models
por: Pollock, Kari, et al.
Publicado: (2016)

Human mesenchymal stem cells in spheroids improve fertility in model animals with damaged endometrium
por: Domnina, Alisa, et al.
Publicado: (2018)

Brain-derived neurotrophic factor promotes immune reconstitution following radiation injury via activation of bone marrow mesenchymal stem cells
por: Sharma, Guru Prasad, et al.
Publicado: (2021)

PEDF – A Noninhibitory Serpin with Neurotrophic Activity
por: Minkevich, N.I., et al.
Publicado: (2010)

Mesenchymal Stem Cells Expressing Brain-Derived Neurotrophic Factor Enhance Endogenous Neurogenesis in an Ischemic Stroke Model
por: Jeong, Chang Hyun, et al.
Publicado: (2014)

Brain-Derived Neurotrophic Factor Levels in Mesenchymal Stem Cell Culture Fluid Under Different Culture Conditions
por: Çiçek, Gülsemin, et al.
Publicado: (2023)

Past and Future of Neurotrophic Growth Factors Therapies in ALS: From Single Neurotrophic Growth Factor to Stem Cells and Human Platelet Lysates
por: Gouel, Flore, et al.
Publicado: (2019)

Aged Human Multipotent Mesenchymal Stromal Cells Can Be Rejuvenated by Neuron-Derived Neurotrophic Factor and Improve Heart Function After Injury
por: Song, Hui-Fang, et al.
Publicado: (2017)

Human Wharton’s jelly mesenchymal stem cells protect axotomized rat retinal ganglion cells via secretion of anti-inflammatory and neurotrophic factors
por: Millán-Rivero, Jose E., et al.
Publicado: (2018)

Topical Application of Human Wharton’s Jelly Mesenchymal Stem Cells Accelerates Mouse Sciatic Nerve Recovery and is Associated with Upregulated Neurotrophic Factor Expression
por: Wang, Aline Yen Ling, et al.
Publicado: (2019)

Effect of aging on behaviour of mesenchymal stem cells
por: Fafián-Labora, Juan Antonio, et al.
Publicado: (2019)

Synergy of human platelet lysate and laminin to enhance the neurotrophic effect of human adipose-derived stem cells
por: di Summa, Pietro G, et al.
Publicado: (2022)

Mesenchymal stem cells with irreversibly arrested proliferation stimulate decidua development in rats
por: Domnina, Alisa P., et al.
Publicado: (2016)

Bone Marrow-Derived Mesenchymal Stem Cells Improve the Functioning of Neurotrophic Factors in a Mouse Model of Diabetic Neuropathy
por: Kim, Bae Jin, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_d27qma5demng6ceb0fhifa8fm7