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INF2 promotes the formation of detyrosinated microtubules necessary for centrosome reorientation in T cells
T cell antigen receptor–proximal signaling components, Rho-family GTPases, and formin proteins DIA1 and FMNL1 have been implicated in centrosome reorientation to the immunological synapse of T lymphocytes. However, the role of these molecules in the reorientation process is not yet defined. Here we...
Autores principales: | Andrés-Delgado, Laura, Antón, Olga M., Bartolini, Francesca, Ruiz-Sáenz, Ana, Correas, Isabel, Gundersen, Gregg G., Alonso, Miguel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444772/ https://www.ncbi.nlm.nih.gov/pubmed/22986496 http://dx.doi.org/10.1083/jcb.201202137 |
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