Cargando…

Gap Detection for Genome-Scale Constraint-Based Models

Constraint-based metabolic models are currently the most comprehensive system-wide models of cellular metabolism. Several challenges arise when building an in silico constraint-based model of an organism that need to be addressed before flux balance analysis (FBA) can be applied for simulations. An...

Descripción completa

Detalles Bibliográficos
Autores principales: Brooks, J. Paul, Burns, William P., Fong, Stephen S., Gowen, Chris M., Roberts, Seth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444828/
https://www.ncbi.nlm.nih.gov/pubmed/22997515
http://dx.doi.org/10.1155/2012/323472