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Gap Detection for Genome-Scale Constraint-Based Models

Constraint-based metabolic models are currently the most comprehensive system-wide models of cellular metabolism. Several challenges arise when building an in silico constraint-based model of an organism that need to be addressed before flux balance analysis (FBA) can be applied for simulations. An...

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Detalles Bibliográficos
Autores principales:	Brooks, J. Paul, Burns, William P., Fong, Stephen S., Gowen, Chris M., Roberts, Seth B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444828/ https://www.ncbi.nlm.nih.gov/pubmed/22997515 http://dx.doi.org/10.1155/2012/323472

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