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Recurrent Syncope in Patients with Carotid Sinus Hypersensitivity
Syncope recurrence in pacemaker-implanted subjects for the cardio-inhibitory response to sinus carotid massage (SCM) was investigated. The study-hypothesis was that recurrences had significant vasodepressor responses that could justify the loss of consciousness. Forty-six patients were enrolled (16...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scholarly Research Network
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444836/ https://www.ncbi.nlm.nih.gov/pubmed/22997591 http://dx.doi.org/10.5402/2012/216206 |
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author | Lagi, Alfonso Cerisano, Sergio Cencetti, Simone |
author_facet | Lagi, Alfonso Cerisano, Sergio Cencetti, Simone |
author_sort | Lagi, Alfonso |
collection | PubMed |
description | Syncope recurrence in pacemaker-implanted subjects for the cardio-inhibitory response to sinus carotid massage (SCM) was investigated. The study-hypothesis was that recurrences had significant vasodepressor responses that could justify the loss of consciousness. Forty-six patients were enrolled (16 patients and 30 controls), followed and revaluated after 5–7 years. At the end of follow-up, significant differences were found between patients and controls in mean SCM SAP (87 versus 106 mmHg) and reduction in mean SCM SAP (59 versus 38 mmHg); in the number of symptomatic subjects soon after SCM (5 versus 1); and in the number of subjects suffering from orthostatic hypotension. A subgroup of 13 patients showed significantly different hypotensive responses to SCM compared with the values observed at study recruitment. The data showed that some subjects with a defined hemodynamic pattern in response to SCM may change their characteristics and have spontaneous and/or provocative symptoms. These data explain the syncopal relapses, and suggest the presence of autonomic dysregulation in individuals with carotid sinus hypersensitivity. |
format | Online Article Text |
id | pubmed-3444836 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | International Scholarly Research Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-34448362012-09-20 Recurrent Syncope in Patients with Carotid Sinus Hypersensitivity Lagi, Alfonso Cerisano, Sergio Cencetti, Simone ISRN Cardiol Research Article Syncope recurrence in pacemaker-implanted subjects for the cardio-inhibitory response to sinus carotid massage (SCM) was investigated. The study-hypothesis was that recurrences had significant vasodepressor responses that could justify the loss of consciousness. Forty-six patients were enrolled (16 patients and 30 controls), followed and revaluated after 5–7 years. At the end of follow-up, significant differences were found between patients and controls in mean SCM SAP (87 versus 106 mmHg) and reduction in mean SCM SAP (59 versus 38 mmHg); in the number of symptomatic subjects soon after SCM (5 versus 1); and in the number of subjects suffering from orthostatic hypotension. A subgroup of 13 patients showed significantly different hypotensive responses to SCM compared with the values observed at study recruitment. The data showed that some subjects with a defined hemodynamic pattern in response to SCM may change their characteristics and have spontaneous and/or provocative symptoms. These data explain the syncopal relapses, and suggest the presence of autonomic dysregulation in individuals with carotid sinus hypersensitivity. International Scholarly Research Network 2012-09-10 /pmc/articles/PMC3444836/ /pubmed/22997591 http://dx.doi.org/10.5402/2012/216206 Text en Copyright © 2012 Alfonso Lagi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Lagi, Alfonso Cerisano, Sergio Cencetti, Simone Recurrent Syncope in Patients with Carotid Sinus Hypersensitivity |
title | Recurrent Syncope in Patients with Carotid Sinus Hypersensitivity |
title_full | Recurrent Syncope in Patients with Carotid Sinus Hypersensitivity |
title_fullStr | Recurrent Syncope in Patients with Carotid Sinus Hypersensitivity |
title_full_unstemmed | Recurrent Syncope in Patients with Carotid Sinus Hypersensitivity |
title_short | Recurrent Syncope in Patients with Carotid Sinus Hypersensitivity |
title_sort | recurrent syncope in patients with carotid sinus hypersensitivity |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444836/ https://www.ncbi.nlm.nih.gov/pubmed/22997591 http://dx.doi.org/10.5402/2012/216206 |
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