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Necrotizing Enterocolitis in Very Low Birth Weight Infants: A Systemic Review
Necrotizing enterocolitis (NEC) is the most common serious gastrointestinal disorder affecting very preterm or very low birth weight infants. The risk is inversely proportional to gestational age and weight at birth. Fetal growth restriction and compromise may be additional specific risk factors. De...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scholarly Research Network
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444861/ https://www.ncbi.nlm.nih.gov/pubmed/22997587 http://dx.doi.org/10.5402/2012/562594 |
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author | Patel, Bhoomika K. Shah, Jigna S. |
author_facet | Patel, Bhoomika K. Shah, Jigna S. |
author_sort | Patel, Bhoomika K. |
collection | PubMed |
description | Necrotizing enterocolitis (NEC) is the most common serious gastrointestinal disorder affecting very preterm or very low birth weight infants. The risk is inversely proportional to gestational age and weight at birth. Fetal growth restriction and compromise may be additional specific risk factors. Despite extensive research and animal studies etiopathogenesis, preventive strategies and management options remain controversial. The present paper reviews the literature for recent advances and newer insights for changing epidemiological trends, pathogenesis, role of inflammatory cytokines, and various preventive and management strategies. |
format | Online Article Text |
id | pubmed-3444861 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | International Scholarly Research Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-34448612012-09-20 Necrotizing Enterocolitis in Very Low Birth Weight Infants: A Systemic Review Patel, Bhoomika K. Shah, Jigna S. ISRN Gastroenterol Review Article Necrotizing enterocolitis (NEC) is the most common serious gastrointestinal disorder affecting very preterm or very low birth weight infants. The risk is inversely proportional to gestational age and weight at birth. Fetal growth restriction and compromise may be additional specific risk factors. Despite extensive research and animal studies etiopathogenesis, preventive strategies and management options remain controversial. The present paper reviews the literature for recent advances and newer insights for changing epidemiological trends, pathogenesis, role of inflammatory cytokines, and various preventive and management strategies. International Scholarly Research Network 2012-09-10 /pmc/articles/PMC3444861/ /pubmed/22997587 http://dx.doi.org/10.5402/2012/562594 Text en Copyright © 2012 B. K. Patel and J. S. Shah. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Patel, Bhoomika K. Shah, Jigna S. Necrotizing Enterocolitis in Very Low Birth Weight Infants: A Systemic Review |
title | Necrotizing Enterocolitis in Very Low Birth Weight Infants: A Systemic Review |
title_full | Necrotizing Enterocolitis in Very Low Birth Weight Infants: A Systemic Review |
title_fullStr | Necrotizing Enterocolitis in Very Low Birth Weight Infants: A Systemic Review |
title_full_unstemmed | Necrotizing Enterocolitis in Very Low Birth Weight Infants: A Systemic Review |
title_short | Necrotizing Enterocolitis in Very Low Birth Weight Infants: A Systemic Review |
title_sort | necrotizing enterocolitis in very low birth weight infants: a systemic review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444861/ https://www.ncbi.nlm.nih.gov/pubmed/22997587 http://dx.doi.org/10.5402/2012/562594 |
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