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Peroxisome proliferator-activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus

BACKGROUND: Status epilepticus induces subcellular changes that may lead to neuronal cell death in the hippocampus. However, the mechanism of seizure-induced neuronal cell death remains unclear. The mitochondrial uncoupling protein 2 (UCP2) is expressed in selected regions of the brain and is emerge...

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Detalles Bibliográficos
Autores principales: Chuang, Yao-Chung, Lin, Tsu-Kung, Huang, Hsuan-Ying, Chang, Wen-Neng, Liou, Chia-Wei, Chen, Shang-Der, Chang, Alice YW, Chan, Samuel HH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444895/
https://www.ncbi.nlm.nih.gov/pubmed/22849356
http://dx.doi.org/10.1186/1742-2094-9-184