Cargando…
Peroxisome proliferator-activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus
BACKGROUND: Status epilepticus induces subcellular changes that may lead to neuronal cell death in the hippocampus. However, the mechanism of seizure-induced neuronal cell death remains unclear. The mitochondrial uncoupling protein 2 (UCP2) is expressed in selected regions of the brain and is emerge...
Autores principales: | Chuang, Yao-Chung, Lin, Tsu-Kung, Huang, Hsuan-Ying, Chang, Wen-Neng, Liou, Chia-Wei, Chen, Shang-Der, Chang, Alice YW, Chan, Samuel HH |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444895/ https://www.ncbi.nlm.nih.gov/pubmed/22849356 http://dx.doi.org/10.1186/1742-2094-9-184 |
Ejemplares similares
-
Seizure-Induced Oxidative Stress in Status Epilepticus: Is Antioxidant Beneficial?
por: Lin, Tsu-Kung, et al.
Publicado: (2020) -
Sirtuin 1 Regulates Mitochondrial Biogenesis and Provides an Endogenous Neuroprotective Mechanism Against Seizure-Induced Neuronal Cell Death in the Hippocampus Following Status Epilepticus
por: Chuang, Yao-Chung, et al.
Publicado: (2019) -
Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Activates Vascular Endothelial Growth Factor That Protects Against Neuronal Cell Death Following Status Epilepticus through PI3K/AKT and MEK/ERK Signaling
por: Huang, Jyun-Bin, et al.
Publicado: (2020) -
Peroxisome proliferator-activated receptor-gamma dependent pathway reduces the phosphorylation of dynamin-related protein 1 and ameliorates hippocampal injury induced by global ischemia in rats
por: Chuang, Yao-Chung, et al.
Publicado: (2016) -
Resveratrol Promotes Mitochondrial Biogenesis and Protects against Seizure-Induced Neuronal Cell Damage in the Hippocampus Following Status Epilepticus by Activation of the PGC-1α Signaling Pathway
por: Chuang, Yao-Chung, et al.
Publicado: (2019)