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Silencing of a large microRNA cluster on human chromosome 14q32 in melanoma: biological effects of mir-376a and mir-376c on insulin growth factor 1 receptor

BACKGROUND: Metastatic melanoma is a devastating disease with limited therapeutic options. MicroRNAs (miRNAs) are small non coding RNA molecules with important roles in post-transcriptional gene expression regulation, whose aberrant expression has been implicated in cancer. RESULTS: We show that the...

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Detalles Bibliográficos
Autores principales:	Zehavi, Liron, Avraham, Roi, Barzilai, Aviv, Bar-Ilan, Dalia, Navon, Roy, Sidi, Yechezkel, Avni, Dror, Leibowitz-Amit, Raya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444916/ https://www.ncbi.nlm.nih.gov/pubmed/22747855 http://dx.doi.org/10.1186/1476-4598-11-44

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