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The i148m Pnpla3 polymorphism influences serum adiponectin in patients with fatty liver and healthy controls

BACKGROUND: Reduced adiponectin is implicated in the pathogenesis of nonalcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH), and the I148M Patatin-like phospholipase domain-containing 3 (PNPLA3) polymorphism predisposes to NAFLD and liver damage progression in NASH and chronic hepatitis...

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Detalles Bibliográficos
Autores principales: Valenti, Luca, Rametta, Raffaela, Ruscica, Massimiliano, Dongiovanni, Paola, Steffani, Liliana, Motta, Benedetta Maria, Canavesi, Elena, Fracanzani, Anna Ludovica, Mozzi, Enrico, Roviaro, Giancarlo, Magni, Paolo, Fargion, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444917/
https://www.ncbi.nlm.nih.gov/pubmed/22898488
http://dx.doi.org/10.1186/1471-230X-12-111