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Rotavirus A-specific single-domain antibodies produced in baculovirus-infected insect larvae are protective in vivo

BACKGROUND: Single-domain antibodies (sdAbs), also known as nanobodies or VHHs, are characterized by high stability and solubility, thus maintaining the affinity and therapeutic value provided by conventional antibodies. Given these properties, VHHs offer a novel alternative to classical antibody ap...

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Detalles Bibliográficos
Autores principales: Gómez-Sebastián, Silvia, Nuñez, Maria C, Garaicoechea, Lorena, Alvarado, Carmen, Mozgovoj, Marina, Lasa, Rodrigo, Kahl, Alan, Wigdorovitz, Andres, Parreño, Viviana, Escribano, José M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444942/
https://www.ncbi.nlm.nih.gov/pubmed/22953695
http://dx.doi.org/10.1186/1472-6750-12-59