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Rotavirus A-specific single-domain antibodies produced in baculovirus-infected insect larvae are protective in vivo
BACKGROUND: Single-domain antibodies (sdAbs), also known as nanobodies or VHHs, are characterized by high stability and solubility, thus maintaining the affinity and therapeutic value provided by conventional antibodies. Given these properties, VHHs offer a novel alternative to classical antibody ap...
Autores principales: | Gómez-Sebastián, Silvia, Nuñez, Maria C, Garaicoechea, Lorena, Alvarado, Carmen, Mozgovoj, Marina, Lasa, Rodrigo, Kahl, Alan, Wigdorovitz, Andres, Parreño, Viviana, Escribano, José M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444942/ https://www.ncbi.nlm.nih.gov/pubmed/22953695 http://dx.doi.org/10.1186/1472-6750-12-59 |
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