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Adipose tissue-derived mesenchymal stem cells: a fat chance of curing kidney disease?
Many kidney diseases are associated with inflammation and altered immune response. Mesenchymal stem cells are known for their anti-inflammation and immune-modulation. Demonstration that phenotype and immunosuppressive ability of adipose tissue-derived mesenchymal stem cells (AD-MSC) are not affected...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445292/ https://www.ncbi.nlm.nih.gov/pubmed/22975993 http://dx.doi.org/10.1038/ki.2012.158 |
| Sumario: | Many kidney diseases are associated with inflammation and altered immune response. Mesenchymal stem cells are known for their anti-inflammation and immune-modulation. Demonstration that phenotype and immunosuppressive ability of adipose tissue-derived mesenchymal stem cells (AD-MSC) are not affected by human kidney disease and uremic serum could have potential clinical significance if autologous AD-MSC can be tested to prove their long-term safety and efficacy in treating kidney disease. |
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