Adipose tissue-derived mesenchymal stem cells: a fat chance of curing kidney disease?

Many kidney diseases are associated with inflammation and altered immune response. Mesenchymal stem cells are known for their anti-inflammation and immune-modulation. Demonstration that phenotype and immunosuppressive ability of adipose tissue-derived mesenchymal stem cells (AD-MSC) are not affected...

Descripción completa

Detalles Bibliográficos
Autor principal: Lin, Fangming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445292/
https://www.ncbi.nlm.nih.gov/pubmed/22975993
http://dx.doi.org/10.1038/ki.2012.158
_version_ 1782243804880830464
author Lin, Fangming
author_facet Lin, Fangming
author_sort Lin, Fangming
collection PubMed
description Many kidney diseases are associated with inflammation and altered immune response. Mesenchymal stem cells are known for their anti-inflammation and immune-modulation. Demonstration that phenotype and immunosuppressive ability of adipose tissue-derived mesenchymal stem cells (AD-MSC) are not affected by human kidney disease and uremic serum could have potential clinical significance if autologous AD-MSC can be tested to prove their long-term safety and efficacy in treating kidney disease.
format Online
Article
Text
id pubmed-3445292
institution National Center for Biotechnology Information
language English
publishDate 2012
record_format MEDLINE/PubMed
spelling pubmed-34452922013-04-01 Adipose tissue-derived mesenchymal stem cells: a fat chance of curing kidney disease? Lin, Fangming Kidney Int Article Many kidney diseases are associated with inflammation and altered immune response. Mesenchymal stem cells are known for their anti-inflammation and immune-modulation. Demonstration that phenotype and immunosuppressive ability of adipose tissue-derived mesenchymal stem cells (AD-MSC) are not affected by human kidney disease and uremic serum could have potential clinical significance if autologous AD-MSC can be tested to prove their long-term safety and efficacy in treating kidney disease. 2012-10 /pmc/articles/PMC3445292/ /pubmed/22975993 http://dx.doi.org/10.1038/ki.2012.158 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Lin, Fangming
Adipose tissue-derived mesenchymal stem cells: a fat chance of curing kidney disease?
title Adipose tissue-derived mesenchymal stem cells: a fat chance of curing kidney disease?
title_full Adipose tissue-derived mesenchymal stem cells: a fat chance of curing kidney disease?
title_fullStr Adipose tissue-derived mesenchymal stem cells: a fat chance of curing kidney disease?
title_full_unstemmed Adipose tissue-derived mesenchymal stem cells: a fat chance of curing kidney disease?
title_short Adipose tissue-derived mesenchymal stem cells: a fat chance of curing kidney disease?
title_sort adipose tissue-derived mesenchymal stem cells: a fat chance of curing kidney disease?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445292/
https://www.ncbi.nlm.nih.gov/pubmed/22975993
http://dx.doi.org/10.1038/ki.2012.158
work_keys_str_mv AT linfangming adiposetissuederivedmesenchymalstemcellsafatchanceofcuringkidneydisease

Ejemplares similares