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Caspase 2 Activation and ER Stress Drive Rapid Jurkat Cell Apoptosis by Clofibrate

Differently from the antiapoptotic action most commonly assigned to peroxisome proliferators (PPs), we demonstrated that some of them, clofibrate (CF) in particular, display clearcut apoptogenic properties on rat hepatoma cell lines. We and others could confirm that CF as well as various other PPs c...

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Detalles Bibliográficos
Autores principales: Penna, Fabio, Pin, Fabrizio, Costamagna, Domiziana, Reffo, Patrizia, Baccino, Francesco Maria, Bonelli, Gabriella, Costelli, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445471/
https://www.ncbi.nlm.nih.gov/pubmed/23028936
http://dx.doi.org/10.1371/journal.pone.0045327

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