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Low Bone Strength Is a Manifestation of Phenylketonuria in Mice and Is Attenuated by a Glycomacropeptide Diet

PURPOSE: Phenylketonuria (PKU), caused by phenylalanine (phe) hydroxylase loss of function mutations, requires a low-phe diet plus amino acid (AA) formula to prevent cognitive impairment. Glycomacropeptide (GMP), a low-phe whey protein, provides a palatable alternative to AA formula. Skeletal fragil...

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Detalles Bibliográficos
Autores principales: Solverson, Patrick, Murali, Sangita G., Litscher, Suzanne J., Blank, Robert D., Ney, Denise M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445501/
https://www.ncbi.nlm.nih.gov/pubmed/23028819
http://dx.doi.org/10.1371/journal.pone.0045165