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Impact of Glucocorticoid Receptor Gene Polymorphisms on the Metabolic Profile of Adult Patients with the Classical Form of 21-Hydroxylase Deficiency

BACKGROUND: CAH patients have an increased risk of cardiovascular disease, and it remains unknown if lifelong glucocorticoid (GC) treatment is a contributing factor. In the general population, glucocorticoid receptor gene (NR3C1) polymorphisms are associated with an adverse metabolic profile. Our ai...

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Detalles Bibliográficos
Autores principales: Moreira, Ricardo P. P., Gomes, Larissa G., Mendonca, Berenice B., Bachega, Tânia A. S. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445550/
https://www.ncbi.nlm.nih.gov/pubmed/23028665
http://dx.doi.org/10.1371/journal.pone.0044893

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