A Complex Interaction between Rickettsia conorii and Dickkopf-1 – Potential Role in Immune Evasion Mechanisms in Endothelial Cells

The pathophysiological hallmark of spotted fever group rickettsioses comprises vascular inflammation. Based on the emerging importance of the wingless (Wnt) pathways in inflammation and vascular biology, we hypothesized that Dickkopf-1 (DKK-1), as a major modulator of Wnt signaling, could be involve...

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Detalles Bibliográficos
Autores principales: Astrup, Elisabeth, Lekva, Tove, Davì, Giovanni, Otterdal, Kari, Santilli, Francesca, Øie, Erik, Halvorsen, Bente, Damås, Jan Kristian, Raoult, Didier, Vitale, Giustina, Olano, Juan P., Ueland, Thor, Aukrust, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445570/
https://www.ncbi.nlm.nih.gov/pubmed/23028464
http://dx.doi.org/10.1371/journal.pone.0043638

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