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Cynoglossus semilaevis ISG15: A Secreted Cytokine-Like Protein That Stimulates Antiviral Immune Response in a LRGG Motif-Dependent Manner

ISG15 is an ubiquitin-like protein that is induced rapidly by interferon stimulation. Like ubiquitin, ISG15 forms covalent conjugates with its target proteins in a process called ISGylation, which in mammals is known to play a role in antiviral immunity. In contrast to mammalian ISG15, the function...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Zhang, Min, Xiao, Zhi-zhong, Sun, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445607/
https://www.ncbi.nlm.nih.gov/pubmed/23028660
http://dx.doi.org/10.1371/journal.pone.0044884

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