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Isolated Hemihyperplasia in an Infant: An Overlooked Sign for Wilms Tumor Development
BACKGROUND: Children with overgrowth syndromes including isolated hemihyperplasia have an increased risk for developing embryonal tumors, particularly Wilms’ tumor and hepatoblastoma. Screening with sonography has been suggested as a method of identifying these tumors while they are still at an earl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tehran University of Medical Sciences
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446009/ https://www.ncbi.nlm.nih.gov/pubmed/23056692 |
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author | Mutafoglu, Kamer Cecen, Emre Cakmakci, Handan |
author_facet | Mutafoglu, Kamer Cecen, Emre Cakmakci, Handan |
author_sort | Mutafoglu, Kamer |
collection | PubMed |
description | BACKGROUND: Children with overgrowth syndromes including isolated hemihyperplasia have an increased risk for developing embryonal tumors, particularly Wilms’ tumor and hepatoblastoma. Screening with sonography has been suggested as a method of identifying these tumors while they are still at an early stage. CASE PRESENTATION: We describe an infant diagnosed with Wilms tumor in whom isolated hemihyperplasia had been overlooked by several physicians prior to the tumor diagnosis. CONCLUSION: We recommend tumor surveillance for all patients with Beckwith-Wiedemann syndrome and isolated hemihyperplasia at least for the first six years of life since full molecular characterization of every patient is not readily available. |
format | Online Article Text |
id | pubmed-3446009 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Tehran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-34460092012-10-09 Isolated Hemihyperplasia in an Infant: An Overlooked Sign for Wilms Tumor Development Mutafoglu, Kamer Cecen, Emre Cakmakci, Handan Iran J Pediatr Case Report BACKGROUND: Children with overgrowth syndromes including isolated hemihyperplasia have an increased risk for developing embryonal tumors, particularly Wilms’ tumor and hepatoblastoma. Screening with sonography has been suggested as a method of identifying these tumors while they are still at an early stage. CASE PRESENTATION: We describe an infant diagnosed with Wilms tumor in whom isolated hemihyperplasia had been overlooked by several physicians prior to the tumor diagnosis. CONCLUSION: We recommend tumor surveillance for all patients with Beckwith-Wiedemann syndrome and isolated hemihyperplasia at least for the first six years of life since full molecular characterization of every patient is not readily available. Tehran University of Medical Sciences 2010-03 /pmc/articles/PMC3446009/ /pubmed/23056692 Text en © 2010 Iranian Journal of Pediatrics & Tehran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Case Report Mutafoglu, Kamer Cecen, Emre Cakmakci, Handan Isolated Hemihyperplasia in an Infant: An Overlooked Sign for Wilms Tumor Development |
title | Isolated Hemihyperplasia in an Infant: An Overlooked Sign for Wilms Tumor Development |
title_full | Isolated Hemihyperplasia in an Infant: An Overlooked Sign for Wilms Tumor Development |
title_fullStr | Isolated Hemihyperplasia in an Infant: An Overlooked Sign for Wilms Tumor Development |
title_full_unstemmed | Isolated Hemihyperplasia in an Infant: An Overlooked Sign for Wilms Tumor Development |
title_short | Isolated Hemihyperplasia in an Infant: An Overlooked Sign for Wilms Tumor Development |
title_sort | isolated hemihyperplasia in an infant: an overlooked sign for wilms tumor development |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446009/ https://www.ncbi.nlm.nih.gov/pubmed/23056692 |
work_keys_str_mv | AT mutafoglukamer isolatedhemihyperplasiainaninfantanoverlookedsignforwilmstumordevelopment AT cecenemre isolatedhemihyperplasiainaninfantanoverlookedsignforwilmstumordevelopment AT cakmakcihandan isolatedhemihyperplasiainaninfantanoverlookedsignforwilmstumordevelopment |