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Cyclosporine in the Treatment of a Case of Fulminant and Refractory Acute Disseminated Encephalomyelitis

BACKGROUND: Acute disseminated encephalomyelitis (ADEM) is a rare, monophasic, demyelinating disease of the CNS which sometimes could be refractory to traditional treatment. CASE PRESENTATION: We present a case of fulminant ADEM which is treated with combination of corticosteroid, intravenous immuno...

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Detalles Bibliográficos
Autores principales: Taghdiri, Mohammd-Mehdi, Amanati, Ali, Abdolkarimi, Babak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446122/
https://www.ncbi.nlm.nih.gov/pubmed/23056845
Descripción
Sumario:BACKGROUND: Acute disseminated encephalomyelitis (ADEM) is a rare, monophasic, demyelinating disease of the CNS which sometimes could be refractory to traditional treatment. CASE PRESENTATION: We present a case of fulminant ADEM which is treated with combination of corticosteroid, intravenous immunoglobulin and cyclosporine. CONCLUSION: Immunosuppressive agents such as cyclosporine may be effective especially in fulminant form of the disease.