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Abdominal Inflammatory Myofibroblastic Tumor: Report on Four Cases and Review of Literature
BACKGROUND: The Abdominal Inflammatory Myofibroblastic Tumor (AIMT) is a rare tumor with unknown etiology which usually occurs in children and adolescents. It is composed of myofibroblastic spindle cells intermixed with inflammatory cells. We present four cases of AIMT. CASES PRESENTATION: We herein...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tehran University of Medical Sciences
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446124/ https://www.ncbi.nlm.nih.gov/pubmed/23056847 |
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author | Mirshemirani, Alireza Tabari, Ahmad Khaleghnejad Sadeghian, Naser Shariat-Torbaghan, Siamak Pourafkari, Marina Mohajerzadeh, Leila |
author_facet | Mirshemirani, Alireza Tabari, Ahmad Khaleghnejad Sadeghian, Naser Shariat-Torbaghan, Siamak Pourafkari, Marina Mohajerzadeh, Leila |
author_sort | Mirshemirani, Alireza |
collection | PubMed |
description | BACKGROUND: The Abdominal Inflammatory Myofibroblastic Tumor (AIMT) is a rare tumor with unknown etiology which usually occurs in children and adolescents. It is composed of myofibroblastic spindle cells intermixed with inflammatory cells. We present four cases of AIMT. CASES PRESENTATION: We herein present four cases of AIMT in different ages (range: 3.5 to 13 years) and in different organs (stomach, periduodenal, mesenteric, and colon). There were two females and two males. The main symptoms were abdominal pain/mass/obstruction, vomiting, and weight loss. In all four patients, diagnosis was made by laparatomy and pathologic examination of excised mass lesion. Three patients underwent complete excision and no residual disease was present, one patient received chemotherapy due to tumor recurrences. The patients were followed up in average for four years. CONCLUSION: As the imaging and laboratory tests are non-specific, the diagnosis of AIMT is rarely made before surgery. AIMT should, therefore, be considered when a mass arises in an unusual location in the pediatric age group. Complete surgical resection should be performed whenever possible and the child should be kept on long-term follow-up. |
format | Online Article Text |
id | pubmed-3446124 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Tehran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-34461242012-10-09 Abdominal Inflammatory Myofibroblastic Tumor: Report on Four Cases and Review of Literature Mirshemirani, Alireza Tabari, Ahmad Khaleghnejad Sadeghian, Naser Shariat-Torbaghan, Siamak Pourafkari, Marina Mohajerzadeh, Leila Iran J Pediatr Case Report BACKGROUND: The Abdominal Inflammatory Myofibroblastic Tumor (AIMT) is a rare tumor with unknown etiology which usually occurs in children and adolescents. It is composed of myofibroblastic spindle cells intermixed with inflammatory cells. We present four cases of AIMT. CASES PRESENTATION: We herein present four cases of AIMT in different ages (range: 3.5 to 13 years) and in different organs (stomach, periduodenal, mesenteric, and colon). There were two females and two males. The main symptoms were abdominal pain/mass/obstruction, vomiting, and weight loss. In all four patients, diagnosis was made by laparatomy and pathologic examination of excised mass lesion. Three patients underwent complete excision and no residual disease was present, one patient received chemotherapy due to tumor recurrences. The patients were followed up in average for four years. CONCLUSION: As the imaging and laboratory tests are non-specific, the diagnosis of AIMT is rarely made before surgery. AIMT should, therefore, be considered when a mass arises in an unusual location in the pediatric age group. Complete surgical resection should be performed whenever possible and the child should be kept on long-term follow-up. Tehran University of Medical Sciences 2011-12 /pmc/articles/PMC3446124/ /pubmed/23056847 Text en © 2011 Iranian Journal of Pediatrics & Tehran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Case Report Mirshemirani, Alireza Tabari, Ahmad Khaleghnejad Sadeghian, Naser Shariat-Torbaghan, Siamak Pourafkari, Marina Mohajerzadeh, Leila Abdominal Inflammatory Myofibroblastic Tumor: Report on Four Cases and Review of Literature |
title | Abdominal Inflammatory Myofibroblastic Tumor: Report on Four Cases and Review of Literature |
title_full | Abdominal Inflammatory Myofibroblastic Tumor: Report on Four Cases and Review of Literature |
title_fullStr | Abdominal Inflammatory Myofibroblastic Tumor: Report on Four Cases and Review of Literature |
title_full_unstemmed | Abdominal Inflammatory Myofibroblastic Tumor: Report on Four Cases and Review of Literature |
title_short | Abdominal Inflammatory Myofibroblastic Tumor: Report on Four Cases and Review of Literature |
title_sort | abdominal inflammatory myofibroblastic tumor: report on four cases and review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446124/ https://www.ncbi.nlm.nih.gov/pubmed/23056847 |
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