A Case of Lipoid Congenital Adrenal Hyperplasia Presenting with Cholestasis

BACKGROUND: Lipoid congenital adrenal hyperplasia, is the rarest and usually the most severe form of adrenal steroidogenic defect,which may presents as infantile cholestasis. CASE PRESENTATION: Here we present a 45 days old infant who came to our attention with cholestasis and severe intractable vom...

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Detalles Bibliográficos
Autores principales: Khodadad, Ahmad, Modaresi, Vajiheh, Kiani, Mohammad-Ali, Rabani, Ali, Pakseresht, Bahar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446141/
https://www.ncbi.nlm.nih.gov/pubmed/23056846
Descripción
Sumario:BACKGROUND: Lipoid congenital adrenal hyperplasia, is the rarest and usually the most severe form of adrenal steroidogenic defect,which may presents as infantile cholestasis. CASE PRESENTATION: Here we present a 45 days old infant who came to our attention with cholestasis and severe intractable vomiting and electrolyte disturbances. Evaluation resulted in diagnosis of congenital adrenal hyperplasia. Hydrocortisone and flodrocortisone improved the symptoms including jaundice and vomiting. Hyponatremia and hyperkalemia also resolved with above mentioned treatment. CONCLUSION: Congenital adrenal hyperplasia as one of the causes of neonatal cholestasis should be kept in mind, whenever there are also electrolytes abnormalities.

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