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Pathologic Evaluation of Appendectomy Specimens in Children: Is Routine Histopatholgic Examination Indicated?

OBJECTIVE: Acute appendicitis is the most common cause of abdominal surgery in children. Similarity between signs and symptoms of appendicitis and other common pediatric illnesses, atypical manifestations of appendicitis in young children, and children's inability to give precise explanation fo...

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Autores principales: Monajemzadeh, Maryam, Hagghi-Ashtiani, Mohammad-Taghi, Montaser-Kouhsari, Laleh, Ahmadi, Hamed, Zargoosh, Heidar, Kalantari, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446148/
https://www.ncbi.nlm.nih.gov/pubmed/23056836
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author Monajemzadeh, Maryam
Hagghi-Ashtiani, Mohammad-Taghi
Montaser-Kouhsari, Laleh
Ahmadi, Hamed
Zargoosh, Heidar
Kalantari, Mehdi
author_facet Monajemzadeh, Maryam
Hagghi-Ashtiani, Mohammad-Taghi
Montaser-Kouhsari, Laleh
Ahmadi, Hamed
Zargoosh, Heidar
Kalantari, Mehdi
author_sort Monajemzadeh, Maryam
collection PubMed
description OBJECTIVE: Acute appendicitis is the most common cause of abdominal surgery in children. Similarity between signs and symptoms of appendicitis and other common pediatric illnesses, atypical manifestations of appendicitis in young children, and children's inability to give precise explanation for their symptoms contribute to considerable delay in proper diagnosis and increased rate of perforation. Current study reports the surgical and pathological findings of appendectomies in the largest Children's Hospital in Iran. It also evaluates whether common protocol for pathologic evaluation following appendectomy is beneficial. METHODS: Pathologic reports of 947 appendectomies, performed with the presumptive diagnosis of acute appendicitis, were gathered. Correlation between surgical and pathologic findings was assessed. Demographic characteristics of patients between surgical and pathological subgroups were also compared. FINDINGS: The mean age of participants was 6.9±3.5 years. Eighty seven (25.5%) children had abnormal pathological findings and normal surgical report. None of miscellaneous findings including appendicular carcinoid tumor 3 (0.3%), oxyuriasis 2 (0.2%), and mycobacterial infection 4 (0.5%) were recognizable during the surgery. Of all pathologically confirmed cases with perforated appendicitis, 9.7% were not detected during the surgery. CONCLUSION: In current study, acute appendicitis was the most common pathological diagnosis, however, high normal appendectomy rate along with noticeable proportion of surgically missed perforated appendicitis and unusual histopathologies strongly supported routine histological examination.
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spelling pubmed-34461482012-10-09 Pathologic Evaluation of Appendectomy Specimens in Children: Is Routine Histopatholgic Examination Indicated? Monajemzadeh, Maryam Hagghi-Ashtiani, Mohammad-Taghi Montaser-Kouhsari, Laleh Ahmadi, Hamed Zargoosh, Heidar Kalantari, Mehdi Iran J Pediatr Original Article OBJECTIVE: Acute appendicitis is the most common cause of abdominal surgery in children. Similarity between signs and symptoms of appendicitis and other common pediatric illnesses, atypical manifestations of appendicitis in young children, and children's inability to give precise explanation for their symptoms contribute to considerable delay in proper diagnosis and increased rate of perforation. Current study reports the surgical and pathological findings of appendectomies in the largest Children's Hospital in Iran. It also evaluates whether common protocol for pathologic evaluation following appendectomy is beneficial. METHODS: Pathologic reports of 947 appendectomies, performed with the presumptive diagnosis of acute appendicitis, were gathered. Correlation between surgical and pathologic findings was assessed. Demographic characteristics of patients between surgical and pathological subgroups were also compared. FINDINGS: The mean age of participants was 6.9±3.5 years. Eighty seven (25.5%) children had abnormal pathological findings and normal surgical report. None of miscellaneous findings including appendicular carcinoid tumor 3 (0.3%), oxyuriasis 2 (0.2%), and mycobacterial infection 4 (0.5%) were recognizable during the surgery. Of all pathologically confirmed cases with perforated appendicitis, 9.7% were not detected during the surgery. CONCLUSION: In current study, acute appendicitis was the most common pathological diagnosis, however, high normal appendectomy rate along with noticeable proportion of surgically missed perforated appendicitis and unusual histopathologies strongly supported routine histological examination. Tehran University of Medical Sciences 2011-12 /pmc/articles/PMC3446148/ /pubmed/23056836 Text en © 2011 Iranian Journal of Pediatrics & Tehran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Monajemzadeh, Maryam
Hagghi-Ashtiani, Mohammad-Taghi
Montaser-Kouhsari, Laleh
Ahmadi, Hamed
Zargoosh, Heidar
Kalantari, Mehdi
Pathologic Evaluation of Appendectomy Specimens in Children: Is Routine Histopatholgic Examination Indicated?
title Pathologic Evaluation of Appendectomy Specimens in Children: Is Routine Histopatholgic Examination Indicated?
title_full Pathologic Evaluation of Appendectomy Specimens in Children: Is Routine Histopatholgic Examination Indicated?
title_fullStr Pathologic Evaluation of Appendectomy Specimens in Children: Is Routine Histopatholgic Examination Indicated?
title_full_unstemmed Pathologic Evaluation of Appendectomy Specimens in Children: Is Routine Histopatholgic Examination Indicated?
title_short Pathologic Evaluation of Appendectomy Specimens in Children: Is Routine Histopatholgic Examination Indicated?
title_sort pathologic evaluation of appendectomy specimens in children: is routine histopatholgic examination indicated?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446148/
https://www.ncbi.nlm.nih.gov/pubmed/23056836
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