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Growth Impairment and Nutritional Status in Children with Chronic Kidney Disease

OBJECTIVE: Malnutrition is closely linked to chronic kidney disease (CKD) in adult patients with poor outcome. But data on pediatric patients is inadequate. The aim of this study was to describe the prevalence of growth failure and malnutrition in pediatric CKD patients and explore the relationship...

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Autores principales: Sozeri, Betul, Mir, Sevgi, Kara, Orhan Deniz, Dincel, Nida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446188/
https://www.ncbi.nlm.nih.gov/pubmed/23056801
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author Sozeri, Betul
Mir, Sevgi
Kara, Orhan Deniz
Dincel, Nida
author_facet Sozeri, Betul
Mir, Sevgi
Kara, Orhan Deniz
Dincel, Nida
author_sort Sozeri, Betul
collection PubMed
description OBJECTIVE: Malnutrition is closely linked to chronic kidney disease (CKD) in adult patients with poor outcome. But data on pediatric patients is inadequate. The aim of this study was to describe the prevalence of growth failure and malnutrition in pediatric CKD patients and explore the relationship of these parameters to each other and to other clinical parameters. METHODS: This study included 42 patients and 29 healthy children matched for age and gender. Patients were classified firstly in age group and secondly in therapy modalities. Nutritional evaluations were performed according to the Kidney Disease Outcomes Quality Initiative guidelines, and we performed adjustments using values from children with the same chronological age as reference. FINDINGS: In pubertal group, the mean height SDS was lower than in pre-pubertal period while it was higher than in early childhood (P=0.4 and P=0.03 respectively). In all groups, 45% of patients had malnutrition: 20 patients on predialysis, 22 patients with end stage renal disease (14 on hemodialysis, and 8 on peritoneal dialysis). The mean weight SDS was lower in end stage renal disease groups (P<0.001). The height SDS was lower in end stage renal disease groups (P<0.001). CONCLUSION: Growth failure and malnutrition remain a significant clinical problem as age and therapy modalities are dependent in children with CKD.
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spelling pubmed-34461882012-10-09 Growth Impairment and Nutritional Status in Children with Chronic Kidney Disease Sozeri, Betul Mir, Sevgi Kara, Orhan Deniz Dincel, Nida Iran J Pediatr Original Article OBJECTIVE: Malnutrition is closely linked to chronic kidney disease (CKD) in adult patients with poor outcome. But data on pediatric patients is inadequate. The aim of this study was to describe the prevalence of growth failure and malnutrition in pediatric CKD patients and explore the relationship of these parameters to each other and to other clinical parameters. METHODS: This study included 42 patients and 29 healthy children matched for age and gender. Patients were classified firstly in age group and secondly in therapy modalities. Nutritional evaluations were performed according to the Kidney Disease Outcomes Quality Initiative guidelines, and we performed adjustments using values from children with the same chronological age as reference. FINDINGS: In pubertal group, the mean height SDS was lower than in pre-pubertal period while it was higher than in early childhood (P=0.4 and P=0.03 respectively). In all groups, 45% of patients had malnutrition: 20 patients on predialysis, 22 patients with end stage renal disease (14 on hemodialysis, and 8 on peritoneal dialysis). The mean weight SDS was lower in end stage renal disease groups (P<0.001). The height SDS was lower in end stage renal disease groups (P<0.001). CONCLUSION: Growth failure and malnutrition remain a significant clinical problem as age and therapy modalities are dependent in children with CKD. Tehran University of Medical Sciences 2011-09 /pmc/articles/PMC3446188/ /pubmed/23056801 Text en © 2011 Iranian Journal of Pediatrics & Tehran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Sozeri, Betul
Mir, Sevgi
Kara, Orhan Deniz
Dincel, Nida
Growth Impairment and Nutritional Status in Children with Chronic Kidney Disease
title Growth Impairment and Nutritional Status in Children with Chronic Kidney Disease
title_full Growth Impairment and Nutritional Status in Children with Chronic Kidney Disease
title_fullStr Growth Impairment and Nutritional Status in Children with Chronic Kidney Disease
title_full_unstemmed Growth Impairment and Nutritional Status in Children with Chronic Kidney Disease
title_short Growth Impairment and Nutritional Status in Children with Chronic Kidney Disease
title_sort growth impairment and nutritional status in children with chronic kidney disease
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446188/
https://www.ncbi.nlm.nih.gov/pubmed/23056801
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