Biomarker discovery in human cerebrospinal fluid: the need for integrative metabolome and proteome databases

The number of metabolites identified in human cerebrospinal fluid (CSF) has steadily increased over the past 5 years, and in this issue of Genome Medicine David Wishart and colleagues provide a comprehensive update that brings the number of metabolites listed in the CSF metabolome database to 476 co...

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Autores principales: Schwarz, Emanuel, Torrey, E Fuller, Guest, Paul C, Bahn, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446267/
https://www.ncbi.nlm.nih.gov/pubmed/22546850
http://dx.doi.org/10.1186/gm338
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author Schwarz, Emanuel
Torrey, E Fuller
Guest, Paul C
Bahn, Sabine
author_facet Schwarz, Emanuel
Torrey, E Fuller
Guest, Paul C
Bahn, Sabine
author_sort Schwarz, Emanuel
collection PubMed
description The number of metabolites identified in human cerebrospinal fluid (CSF) has steadily increased over the past 5 years, and in this issue of Genome Medicine David Wishart and colleagues provide a comprehensive update that brings the number of metabolites listed in the CSF metabolome database to 476 compounds. There is now a need for an integrative metabolome-proteome CSF database to maximize the impact of this achievement in biomedical research. Only by such efforts can we hope to unravel the complexity of molecular pathophysiological processes.
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spelling pubmed-34462672012-09-20 Biomarker discovery in human cerebrospinal fluid: the need for integrative metabolome and proteome databases Schwarz, Emanuel Torrey, E Fuller Guest, Paul C Bahn, Sabine Genome Med Research Highlight The number of metabolites identified in human cerebrospinal fluid (CSF) has steadily increased over the past 5 years, and in this issue of Genome Medicine David Wishart and colleagues provide a comprehensive update that brings the number of metabolites listed in the CSF metabolome database to 476 compounds. There is now a need for an integrative metabolome-proteome CSF database to maximize the impact of this achievement in biomedical research. Only by such efforts can we hope to unravel the complexity of molecular pathophysiological processes. BioMed Central 2012-04-30 /pmc/articles/PMC3446267/ /pubmed/22546850 http://dx.doi.org/10.1186/gm338 Text en Copyright ©2012 BioMed Central Ltd.
spellingShingle Research Highlight
Schwarz, Emanuel
Torrey, E Fuller
Guest, Paul C
Bahn, Sabine
Biomarker discovery in human cerebrospinal fluid: the need for integrative metabolome and proteome databases
title Biomarker discovery in human cerebrospinal fluid: the need for integrative metabolome and proteome databases
title_full Biomarker discovery in human cerebrospinal fluid: the need for integrative metabolome and proteome databases
title_fullStr Biomarker discovery in human cerebrospinal fluid: the need for integrative metabolome and proteome databases
title_full_unstemmed Biomarker discovery in human cerebrospinal fluid: the need for integrative metabolome and proteome databases
title_short Biomarker discovery in human cerebrospinal fluid: the need for integrative metabolome and proteome databases
title_sort biomarker discovery in human cerebrospinal fluid: the need for integrative metabolome and proteome databases
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446267/
https://www.ncbi.nlm.nih.gov/pubmed/22546850
http://dx.doi.org/10.1186/gm338
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