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A recurrent fusion gene in high-grade endometrial stromal sarcoma: a new tool for diagnosis and therapy?

High-grade endometrial stromal sarcomas (ESSs) are an aggressive group of endometrial stromal tumors. A recent study described a recurrent chromosomal translocation (t(10;17)) occurring in ESS, which joins the gene 14-3-3ε with either FAM22A or FAM22B. Expression of the resulting fusion gene leads t...

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Detalles Bibliográficos
Autores principales: Ried, Thomas, Gaiser, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446270/
https://www.ncbi.nlm.nih.gov/pubmed/22429906
http://dx.doi.org/10.1186/gm319

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