High-throughput sequencing to decipher the genetic heterogeneity of deafness

Identifying genes causing non-syndromic hearing loss has been challenging using traditional approaches. We describe the impact that high-throughput sequencing approaches are having in discovery of genes related to hearing loss and the implications for clinical diagnosis.

Detalles Bibliográficos
Autores principales: Brownstein, Zippora, Bhonker, Yoni, Avraham, Karen B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446284/
https://www.ncbi.nlm.nih.gov/pubmed/22647651
http://dx.doi.org/10.1186/gb-2012-13-5-245
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author Brownstein, Zippora
Bhonker, Yoni
Avraham, Karen B
author_facet Brownstein, Zippora
Bhonker, Yoni
Avraham, Karen B
author_sort Brownstein, Zippora
collection PubMed
description Identifying genes causing non-syndromic hearing loss has been challenging using traditional approaches. We describe the impact that high-throughput sequencing approaches are having in discovery of genes related to hearing loss and the implications for clinical diagnosis.
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spelling pubmed-34462842013-05-29 High-throughput sequencing to decipher the genetic heterogeneity of deafness Brownstein, Zippora Bhonker, Yoni Avraham, Karen B Genome Biol Review Identifying genes causing non-syndromic hearing loss has been challenging using traditional approaches. We describe the impact that high-throughput sequencing approaches are having in discovery of genes related to hearing loss and the implications for clinical diagnosis. BioMed Central 2012 2012-05-29 /pmc/articles/PMC3446284/ /pubmed/22647651 http://dx.doi.org/10.1186/gb-2012-13-5-245 Text en Copyright ©2012 BioMed Central Ltd.
spellingShingle Review
Brownstein, Zippora
Bhonker, Yoni
Avraham, Karen B
High-throughput sequencing to decipher the genetic heterogeneity of deafness
title High-throughput sequencing to decipher the genetic heterogeneity of deafness
title_full High-throughput sequencing to decipher the genetic heterogeneity of deafness
title_fullStr High-throughput sequencing to decipher the genetic heterogeneity of deafness
title_full_unstemmed High-throughput sequencing to decipher the genetic heterogeneity of deafness
title_short High-throughput sequencing to decipher the genetic heterogeneity of deafness
title_sort high-throughput sequencing to decipher the genetic heterogeneity of deafness
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446284/
https://www.ncbi.nlm.nih.gov/pubmed/22647651
http://dx.doi.org/10.1186/gb-2012-13-5-245
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