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Genetic architecture of body size in mammals
Much of the heritability for human stature is caused by mutations of small-to-medium effect. This is because detrimental pleiotropy restricts large-effect mutations to very low frequencies.
Autores principales: | Kemper, Kathryn E, Visscher, Peter M, Goddard, Michael E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446298/ https://www.ncbi.nlm.nih.gov/pubmed/22546202 http://dx.doi.org/10.1186/gb-2012-13-4-244 |
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