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High levels of RNA-editing site conservation amongst 15 laboratory mouse strains
BACKGROUND: Adenosine-to-inosine (A-to-I) editing is a site-selective post-transcriptional alteration of double-stranded RNA by ADAR deaminases that is crucial for homeostasis and development. Recently the Mouse Genomes Project generated genome sequences for 17 laboratory mouse strains and rich cata...
Autores principales: | Danecek, Petr, Nellåker, Christoffer, McIntyre, Rebecca E, Buendia-Buendia, Jorge E, Bumpstead, Suzannah, Ponting, Chris P, Flint, Jonathan, Durbin, Richard, Keane, Thomas M, Adams, David J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446300/ https://www.ncbi.nlm.nih.gov/pubmed/22524474 http://dx.doi.org/10.1186/gb-2012-13-4-r26 |
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