Global mRNA decay analysis at single nucleotide resolution reveals segmental and positional degradation patterns in a Gram-positive bacterium

BACKGROUND: Recent years have shown a marked increase in the use of next-generation sequencing technologies for quantification of gene expression (RNA sequencing, RNA-Seq). The expression level of a gene is a function of both its rate of transcription and RNA decay, and the influence of mRNA decay r...

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Detalles Bibliográficos
Autores principales: Kristoffersen, Simen M, Haase, Chad, Weil, M Ryan, Passalacqua, Karla D, Niazi, Faheem, Hutchison, Stephen K, Desany, Brian, Kolstø, Anne-Brit, Tourasse, Nicolas J, Read, Timothy D, Økstad, Ole Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446304/
https://www.ncbi.nlm.nih.gov/pubmed/22537947
http://dx.doi.org/10.1186/gb-2012-13-4-r30

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