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The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities

Longitudinal cohort studies are ideal for investigating how epigenetic patterns change over time and relate to changing exposure patterns and the development of disease. We highlight the challenges and opportunities in this approach.

Detalles Bibliográficos
Autores principales: Ng, Jane WY, Barrett, Laura M, Wong, Andrew, Kuh, Diana, Smith, George Davey, Relton, Caroline L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446311/
https://www.ncbi.nlm.nih.gov/pubmed/22747597
http://dx.doi.org/10.1186/gb-2012-13-6-246
Descripción
Sumario:Longitudinal cohort studies are ideal for investigating how epigenetic patterns change over time and relate to changing exposure patterns and the development of disease. We highlight the challenges and opportunities in this approach.