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m:Explorer: multinomial regression models reveal positive and negative regulators of longevity in yeast quiescence

We developed m:Explorer for identifying process-specific transcription factors (TFs) from multiple genome-wide sources, including transcriptome, DNA-binding and chromatin data. m:Explorer robustly outperforms similar techniques in finding cell cycle TFs in Saccharomyces cerevisiae. We predicted and...

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Detalles Bibliográficos
Autores principales: Reimand, Jüri, Aun, Anu, Vilo, Jaak, Vaquerizas, Juan M, Sedman, Juhan, Luscombe, Nicholas M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446321/
https://www.ncbi.nlm.nih.gov/pubmed/22720667
http://dx.doi.org/10.1186/gb-2012-13-6-r55